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Cocaine (COC) Urine Test Kits is a rapid, lateral flow diagnostic test intended to evaluate the usage of cocaine by detecting benzoylecgonine, a metabolite of cocaine, in human urine at a cut-off level of 300 ng/ml. The accuracy rate of this test is >97.8%. This test is US FDA Cleared, CE Marked and is available in some OTC Cleared/CLIA-Waived formats.
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Cocaine is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "Coca" in addition to the alkaloid suffix -ine, forming cocaine.
Cocaine is a powerfully addictive stimulant that directly affects the brain. Cocaine was labeled the drug of the 1980s and '90s, because of its extensive popularity and use during this period. However, cocaine is not a new drug. In fact, it is one of the oldest known drugs. The pure chemical, cocaine hydrochloride, has been an abused substance for more than 100 years, and coca leaves, the source of cocaine, have been ingested for thousands of years. Pure cocaine was first extracted from the leaf of the Erythroxylon coca bush, which grows primarily in Peru and Bolivia, in the mid-19th century. In the early 1900s, it became the main stimulant drug used in most of the tonics/elixirs that were developed to treat a wide variety of illnesses. Today, cocaine is a Schedule II drug, meaning that it has high potential for abuse, but can be administered by a doctor for legitimate medical uses, such as local anesthesia for some eye, ear, and throat surgeries.
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Assuming decriminalisation or legalisation are not on the table, targeting suppliers in an illegal market such as this is unlikely to eradicate the problem. One possible complement would be to focus on consumer awareness and information - an anti-cocaine campaign that tries to reduce demand. Something that pushes buyers to face up to these not-so-hidden costs. If we’re a society that worries about eating free range chicken, drinking fair trade coffee and buying shoes and jeans that were not put together by sweatshop labour? Well, we’d better worry about the real cost of cocaine, too.
1 gram = .03 ounces
3.5 grams = 1/8 of an ounce "Eight Ball"
7 grams = Quarter ounce (two eight
14 grams = Half ounce
21 grams = Third of an ounce
28.3 grams = Ounce "an O"
62 grams = 2.18 ounces "Sixty Two"
125 grams = 4.40 ounces "Big Eight"
(Eighth of a kilo)
250 grams = 8.81 ounces "Quarter
500 grams = 17.63 ounces "Half Kilo"
750 grams = 26.45 ounces "Three
quarters of a kilo"
1000 grams = 35.27 ounces "One Kilo"
What’s the market price for cocaine?So how much do we pay for our cocaine? By international standards, cocaine prices in Australia are high. In the US you can expect to pay a WHOLESALE price of around 20 US dollars per gram. In Australia, it’s been rare to see that wholesale price fall below 200 to 250 Australian dollars per gram, depending on purity. Does that price reflect the real cost of cocaine? No. Not by a long shot. Economists define the real cost of a good or service not just in terms of the cost paid by the buyer, but also the cost to other parties affected by the transaction - the negative externalities. This is why as institutions like the National Drug and Alcohol Research Centre try to estimate the social cost of drug use. It’s also important to bear in mind the costs and consequences associated not just with its use, but also with its supply. There are negative externalities on the supply side of goods and services. In the context of illegal markets, consider the introductory sequence to Lord of War (a film of debatable quality modelled loosely on the story of Victor Bout), which emphasises the role not just of the user, but also of the production, transportation and distribution of a bullet before it is fired. We know about campaigns against sweatshop labour or initiatives like Oxfam’s Fair Trade which try to raise awareness about costs and consequences in relation to food and clothing. So when it comes to cocaine, how does it get to Australia, and what other costs - whether monetary or not - are created along the way?
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Cocaine hydrochloride It uses “coke”, “C”, “snow”, “flake” or “blow” as street names. Characterized as white and powdery in consistency, it comes in the form of salt, particularly hydrochloride salt, which is quite soluble in water.It is usually either sniffed (snorted) or injected.This substance cannot be smoked, for it will be destroyed when burned. Freebase Cocaine Chemically modified, it is otherwise known as alkaloidal cocaine. As base form of cocaine, it is practically insoluble in water.This type is administered by smoking, and usually makes the user feel ”high” immediately by being immersed to the brain very quickly.It then releases the metabolite methylecgonidine, which is not only cardiotoxic, but also detrimental to the pulmonary and hepatic tissues.
Crack Cocaine A modified type of freebase cocaine, it is usually in the form of small crystals or rocks, very hard and brittle, and off-white to brown in color Also used for smoking, it stimulates the brain almost instantly.[9, 10, 11] Routes of Administration
Oral “Numbies”, “gummers” and “cocoa puffs” are usually used.Cocaine powder is usually rubbed along the gum lines or smoked onto a cigarette filter, numbing the oral cavity. This can also be exemplified by snow bombs, wherein a small amount of cocaine is wrapped up in a rolling paper and is swallowed.Coca leaves may also be chewed, with its juices absorbed and ingested.Once cocaine is orally administered, it will take around 30 minutes before it reaches the bloodstream.
Insufflation Also known as snorting, sniffing or blowing, it is the most common method for ingesting recreational cocaine.In this route, approximately 30-60% of the alkaloid is absorbed through mucous membranes of the sinuses.The average time with which the sniffed cocaine peaks in the blood is estimated to be around 14 to 15 minutes. Injection Cocaine injection provides the highest blood levels of drug in the shortest amount of time. Within only 3 minutes of administration, symptoms of euphoria can manifest.
Inhalation This can be done either by heating the solid drug and inhaling its vapor, or by smoking freebase or crack form using a small glass tube pipe.Effects of which may last for only 5 to 15 minutes. Suppository Otherwise known as plugging, this method uses an oral syringe. Dissolved cocaine is withdrawn to the syringe and inserted into the anus or vagina.[9, 12,13]
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Cocaine is a strong central nervous system stimulant that increases levels of the neurotransmitter dopamine in brain circuits regulating pleasure and movement. Normally, dopamine is released by neurons in these circuits in response to potential rewards (like the smell of good food) and then recycled back into the cell that released it, thus shutting off the signal between neurons. Cocaine prevents the dopamine from being recycled, causing excessive amounts to build up in the synapse, or junction between neurons. This amplifies the dopamine signal and ultimately disrupts normal brain communication. It is this flood of dopamine that causes cocaine’s characteristic high. With repeated use, cocaine can cause long-term changes in the brain’s reward system as well as other brain systems, which may lead to addiction. With repeated use, tolerance to cocaine also often develops; many cocaine abusers report that they seek but fail to achieve as much pleasure as they did from their first exposure. Some users will increase their dose in an attempt to intensify and prolong their high, but this can also increase the risk of adverse psychological or physiological effects.
The powdered form of cocaine is either inhaled through the nose (snorted), where it is absorbed through the nasal tissue, or dissolved in water and injected into the bloodstream.Crack is a form of cocaine that has been processed to make a rock crystal (also called “freebase cocaine”) that can be smoked. The crystal is heated to produce vapors that are absorbed into the blood-stream through the lungs. (The term “crack” refers to the crackling sound produced by the rock as it is heated.)
The intensity and duration of cocaine’s pleasurable effects depend on the way it is administered. Injecting or smoking cocaine delivers the drug rapidly into the bloodstream and brain, producing a quicker and stronger but shorter-lasting high than snorting. The high from snorting cocaine may last 15 to 30 minutes; the high from smoking may last 5 to 10 minutes.
In order to sustain their high, people who use cocaine often use the drug in a binge pattern-taking the drug repeatedly within a relatively short period of time, at increasingly higher doses. This practice can easily lead to addiction, a chronic relapsing disease caused by changes in the brain and characterized by uncontrollable drug-seeking no matter the consequences.
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